Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New Guinea

BACKGROUND: Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at the codon 76. Previous studies have shown that microsatellite (MS) haplotype variation can be used to...

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Detalles Bibliográficos
Autores principales: DaRe, Jeana T, Mehlotra, Rajeev K, Michon, Pascal, Mueller, Ivo, Reeder, John, Sharma, Yagya D, Stoneking, Mark, Zimmerman, Peter A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838424/
https://www.ncbi.nlm.nih.gov/pubmed/17376240
http://dx.doi.org/10.1186/1475-2875-6-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838424/
https://www.ncbi.nlm.nih.gov/pubmed/17376240
http://dx.doi.org/10.1186/1475-2875-6-34

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