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Evaluation of the OPTC gene in primary open angle glaucoma: functional significance of a silent change
BACKGROUND: We investigated the molecular basis of primary open-angle glaucoma (POAG) using Opticin (OPTC) as a candidate gene on the basis of its expression in the trabecular meshwork cells involved in the disease pathogenesis. Two hundred POAG patients and 100 controls were enrolled in this study....
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838427/ https://www.ncbi.nlm.nih.gov/pubmed/17359525 http://dx.doi.org/10.1186/1471-2199-8-21 |