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Evaluation of the OPTC gene in primary open angle glaucoma: functional significance of a silent change

BACKGROUND: We investigated the molecular basis of primary open-angle glaucoma (POAG) using Opticin (OPTC) as a candidate gene on the basis of its expression in the trabecular meshwork cells involved in the disease pathogenesis. Two hundred POAG patients and 100 controls were enrolled in this study....

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Detalles Bibliográficos
Autores principales: Acharya, Moulinath, Mookherjee, Suddhasil, Bhattacharjee, Ashima, Thakur, Sanjay KD, Bandyopadhyay, Arun K, Sen, Abhijit, Chakrabarti, Subhabrata, Ray, Kunal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838427/
https://www.ncbi.nlm.nih.gov/pubmed/17359525
http://dx.doi.org/10.1186/1471-2199-8-21