Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation

BACKGROUND: The insulin-like growth factor 1 receptor (IGF-1R) plays numerous crucial roles in cancer biology. The majority of knowledge on IGF-1R signaling is concerned with its role in the activation of the canonical phosphatidyl inositol-3 kinase (PI3K)/Akt and MAPK/ERK pathways. However, the rol...

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Detalles Bibliográficos
Autores principales: Sehat, Bita, Andersson, Sandra, Vasilcanu, Radu, Girnita, Leonard, Larsson, Olle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838569/
https://www.ncbi.nlm.nih.gov/pubmed/17406664
http://dx.doi.org/10.1371/journal.pone.0000340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838569/
https://www.ncbi.nlm.nih.gov/pubmed/17406664
http://dx.doi.org/10.1371/journal.pone.0000340

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