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Tumor-specific T cells signal tumor destruction via the lymphotoxin β receptor

BACKGROUND: Previously, we reported that adoptively transferred perforin k/o (PKO), and IFN-γ k/o (GKO), or perforin/IFN-γ double k/o (PKO/GKO) effector T cells mediated regression of B16BL6-D5 (D5) pulmonary metastases and showed that TNF receptor signaling played a critical role in mediating tumor...

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Detalles Bibliográficos
Autores principales: Winter, Hauke, van den Engel, Natasja K, Poehlein, Christian H, Hatz, Rudolf A, Fox, Bernard A, Hu, Hong-Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838896/
https://www.ncbi.nlm.nih.gov/pubmed/17355640
http://dx.doi.org/10.1186/1479-5876-5-14