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Human GLI3 Intragenic Conserved Non-Coding Sequences Are Tissue-Specific Enhancers

The zinc-finger transcription factor GLI3 is a key regulator of development, acting as a primary transducer of Sonic hedgehog (SHH) signaling in a combinatorial context dependent fashion controlling multiple patterning steps in different tissues/organs. A tight temporal and spatial control of gene e...

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Detalles Bibliográficos
Autores principales: Abbasi, Amir Ali, Paparidis, Zissis, Malik, Sajid, Goode, Debbie K., Callaway, Heather, Elgar, Greg, Grzeschik, Karl-Heinz
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838922/
https://www.ncbi.nlm.nih.gov/pubmed/17426814
http://dx.doi.org/10.1371/journal.pone.0000366