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Inhibition of Hippocampal Matrix Metalloproteinase-3 and -9 Disrupts Spatial Memory

Memory consolidation requires synaptic reconfiguration dependent upon extracellular matrix (ECM) molecules interacting with cell adhesion molecules. Matrix metalloproteinase (MMP) activity is responsible for transient alterations in the ECM that may be prerequisite to hippocampal-dependent learning....

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Detalles Bibliográficos
Autores principales: Wright, John W., Brown, Travis E., Harding, Joseph W.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838960/
https://www.ncbi.nlm.nih.gov/pubmed/17502908
http://dx.doi.org/10.1155/2007/73813