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Normalization of boutique two-color microarrays with a high proportion of differentially expressed probes
Normalization is critical for removing systematic variation from microarray data. For two-color microarray platforms, intensity-dependent lowess normalization is commonly used to correct relative gene expression values for biases. Here we outline a normalization method for use when the assumptions o...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839120/ https://www.ncbi.nlm.nih.gov/pubmed/17204140 http://dx.doi.org/10.1186/gb-2007-8-1-r2 |