Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons

BACKGROUND: Genomic comparisons between human and distant, non-primate mammals are commonly used to identify cis-regulatory elements based on constrained sequence evolution. However, these methods fail to detect functional elements that are too weakly conserved among mammals to distinguish them from...

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Detalles Bibliográficos
Autores principales: Wang, Qian-fei, Prabhakar, Shyam, Chanan, Sumita, Cheng, Jan-Fang, Rubin, Edward M, Boffelli, Dario
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839124/
https://www.ncbi.nlm.nih.gov/pubmed/17201929
http://dx.doi.org/10.1186/gb-2007-8-1-r1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839124/
https://www.ncbi.nlm.nih.gov/pubmed/17201929
http://dx.doi.org/10.1186/gb-2007-8-1-r1

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