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Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons
BACKGROUND: Genomic comparisons between human and distant, non-primate mammals are commonly used to identify cis-regulatory elements based on constrained sequence evolution. However, these methods fail to detect functional elements that are too weakly conserved among mammals to distinguish them from...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839124/ https://www.ncbi.nlm.nih.gov/pubmed/17201929 http://dx.doi.org/10.1186/gb-2007-8-1-r1 |