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Clustering of genes into regulons using integrated modeling-COGRIM

We present a Bayesian hierarchical model and Gibbs Sampling implementation that integrates gene expression, ChIP binding, and transcription factor motif data in a principled and robust fashion. COGRIM was applied to both unicellular and mammalian organisms under different scenarios of available data...

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Detalles Bibliográficos
Autores principales: Chen, Guang, Jensen, Shane T, Stoeckert, Christian J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839128/
https://www.ncbi.nlm.nih.gov/pubmed/17204163
http://dx.doi.org/10.1186/gb-2007-8-1-r4