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The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts

The clinical effects of hypokalemia including action potential prolongation and arrhythmogenicity suppressible by lidocaine were reproduced in hypokalemic (3.0 mM K(+)) Langendorff-perfused murine hearts before and after exposure to lidocaine (10 μM). Novel limiting criteria for local and transmural...

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Detalles Bibliográficos
Autores principales: Sabir, Ian N., Fraser, James A., Killeen, Matthew J., Grace, Andrew A., Huang, Christopher L.-H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839769/
https://www.ncbi.nlm.nih.gov/pubmed/17295037
http://dx.doi.org/10.1007/s00424-007-0217-3