Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart

BACKGROUND: Folate is essential for cellular proliferation and tissue regeneration. As mammalian cells cannot synthesize folates de novo, tightly regulated cellular uptake processes have evolved to sustain sufficient levels of intracellular tetrahydrofolate cofactors to support biosynthesis of purin...

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Detalles Bibliográficos
Autores principales: Maddox, Dennis M, Manlapat, Anna, Roon, Penny, Prasad, Puttur, Ganapathy, Vadivel, Smith, Sylvia B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC184426/
https://www.ncbi.nlm.nih.gov/pubmed/12887734
http://dx.doi.org/10.1186/1471-213X-3-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC184426/
https://www.ncbi.nlm.nih.gov/pubmed/12887734
http://dx.doi.org/10.1186/1471-213X-3-6

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