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Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila
BACKGROUND: The Ras-related GTPase, Rheb, regulates the growth of animal cells. Genetic and biochemical tests place Rheb upstream of the target of rapamycin (TOR) protein kinase, and downstream of the tuberous sclerosis complex (TSC1/TSC2) and the insulin-signaling pathway. TOR activity is regulated...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847425/ https://www.ncbi.nlm.nih.gov/pubmed/17371599 http://dx.doi.org/10.1186/1741-7007-5-10 |