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Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila

BACKGROUND: The Ras-related GTPase, Rheb, regulates the growth of animal cells. Genetic and biochemical tests place Rheb upstream of the target of rapamycin (TOR) protein kinase, and downstream of the tuberous sclerosis complex (TSC1/TSC2) and the insulin-signaling pathway. TOR activity is regulated...

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Detalles Bibliográficos
Autores principales: Hall, Dayna J, Grewal, Savraj S, de la Cruz, Aida Flor A, Edgar, Bruce A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847425/
https://www.ncbi.nlm.nih.gov/pubmed/17371599
http://dx.doi.org/10.1186/1741-7007-5-10