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C-type natriuretic peptide regulates endochondral bone growth through p38 MAP kinase-dependent and – independent pathways

BACKGROUND: C-type natriuretic peptide (CNP) has recently been identified as an important anabolic regulator of endochondral bone growth, but the molecular mechanisms mediating its effects are not completely understood. RESULTS: We demonstrate in a tibia organ culture system that pharmacological inh...

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Detalles Bibliográficos
Autores principales: Agoston, Hanga, Khan, Sameena, James, Claudine G, Gillespie, J Ryan, Serra, Rosa, Stanton, Lee-Anne, Beier, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847438/
https://www.ncbi.nlm.nih.gov/pubmed/17374144
http://dx.doi.org/10.1186/1471-213X-7-18