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Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program

BACKGROUND: Aging has been associated with widespread changes at the gene expression level in multiple mammalian tissues. We have used high density oligonucleotide arrays and novel statistical methods to identify specific transcriptional classes that may uncover biological processes that play a cent...

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Detalles Bibliográficos
Autores principales: Edwards, Michael G, Anderson, Rozalyn M, Yuan, Ming, Kendziorski, Christina M, Weindruch, Richard, Prolla, Tomas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847444/
https://www.ncbi.nlm.nih.gov/pubmed/17381838
http://dx.doi.org/10.1186/1471-2164-8-80