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Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease

BACKGROUND: The pathological hallmarks of transmissible spongiform encephalopathy (TSE) diseases are the deposition of a misfolded form of a host-encoded protein (PrP(res)), marked astrocytosis, microglial activation and spongiosis. The development of powerful gene based technologies has permitted i...

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Detalles Bibliográficos
Autores principales: Stobart, Michael J, Parchaliuk, Debra, Simon, Sharon LR, LeMaistre, Jillian, Lazar, Jozef, Rubenstein, Richard, Knox, J David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847514/
https://www.ncbi.nlm.nih.gov/pubmed/17367538
http://dx.doi.org/10.1186/1750-1326-2-5