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Differential expression of interferon responsive genes in rodent models of transmissible spongiform encephalopathy disease
BACKGROUND: The pathological hallmarks of transmissible spongiform encephalopathy (TSE) diseases are the deposition of a misfolded form of a host-encoded protein (PrP(res)), marked astrocytosis, microglial activation and spongiosis. The development of powerful gene based technologies has permitted i...
Autores principales: | Stobart, Michael J, Parchaliuk, Debra, Simon, Sharon LR, LeMaistre, Jillian, Lazar, Jozef, Rubenstein, Richard, Knox, J David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847514/ https://www.ncbi.nlm.nih.gov/pubmed/17367538 http://dx.doi.org/10.1186/1750-1326-2-5 |
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