Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis

As a result of a chemical genetic screen for modulators of metalloprotease activity, we report that 2-mercaptopyridine-N-oxide induces a conspicuous undulating notochord defect in zebrafish embryos, a phenocopy of the leviathan mutant. The location of the chemically-induced wavy notochord correlated...

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Detalles Bibliográficos
Autores principales: Anderson, Carrie, Bartlett, Stephen J., Gansner, John M., Wilson, Duncan, He, Ling, Gitlin, Jonathan D., Kelsh, Robert N., Dowden, James
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847539/
https://www.ncbi.nlm.nih.gov/pubmed/17216056
http://dx.doi.org/10.1039/b613673g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847539/
https://www.ncbi.nlm.nih.gov/pubmed/17216056
http://dx.doi.org/10.1039/b613673g

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