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Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis
As a result of a chemical genetic screen for modulators of metalloprotease activity, we report that 2-mercaptopyridine-N-oxide induces a conspicuous undulating notochord defect in zebrafish embryos, a phenocopy of the leviathan mutant. The location of the chemically-induced wavy notochord correlated...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847539/ https://www.ncbi.nlm.nih.gov/pubmed/17216056 http://dx.doi.org/10.1039/b613673g |