CTG Trinucleotide Repeat “Big Jumps”: Large Expansions, Small Mice

Trinucleotide repeat expansions are the genetic cause of numerous human diseases, including fragile X mental retardation, Huntington disease, and myotonic dystrophy type 1. Disease severity and age of onset are critically linked to expansion size. Previous mouse models of repeat instability have not...

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Detalles Bibliográficos
Autores principales: Gomes-Pereira, Mário, Foiry, Laurent, Nicole, Annie, Huguet, Aline, Junien, Claudine, Munnich, Arnold, Gourdon, Geneviève
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847694/
https://www.ncbi.nlm.nih.gov/pubmed/17411343
http://dx.doi.org/10.1371/journal.pgen.0030052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847694/
https://www.ncbi.nlm.nih.gov/pubmed/17411343
http://dx.doi.org/10.1371/journal.pgen.0030052

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