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Phase 1 Study of Two Merozoite Surface Protein 1 (MSP1(42)) Vaccines for Plasmodium falciparum Malaria

OBJECTIVES: To assess the safety and immunogenicity of two vaccines, MSP1(42)-FVO/Alhydrogel and MSP1(42)-3D7/Alhydrogel, targeting blood-stage Plasmodium falciparum parasites. DESIGN: A Phase 1 open-label, dose-escalating study. SETTING: Quintiles Phase 1 Services, Lenexa, Kansas between July 2004...

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Detalles Bibliográficos
Autores principales: Malkin, Elissa, Long, Carole A, Stowers, Anthony W, Zou, Lanling, Singh, Sanjay, MacDonald, Nicholas J, Narum, David L, Miles, Aaron P, Orcutt, Andrew C, Muratova, Olga, Moretz, Samuel E, Zhou, Hong, Diouf, Ababacar, Fay, Michael, Tierney, Eveline, Leese, Philip, Mahanty, Siddhartha, Miller, Louis H, Saul, Allan, Martin, Laura B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847697/
https://www.ncbi.nlm.nih.gov/pubmed/17415408
http://dx.doi.org/10.1371/journal.pctr.0020012