Integration of Genome and Chromatin Structure with Gene Expression Profiles To Predict c-MYC Recognition Site Binding and Function

The MYC genes encode nuclear sequence specific–binding DNA-binding proteins that are pleiotropic regulators of cellular function, and the c-MYC proto-oncogene is deregulated and/or mutated in most human cancers. Experimental studies of MYC binding to the genome are not fully consistent. While many c...

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Detalles Bibliográficos
Autores principales: Chen, Yili, Blackwell, Thomas W, Chen, Ji, Gao, Jing, Lee, Angel W, States, David J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847699/
https://www.ncbi.nlm.nih.gov/pubmed/17411336
http://dx.doi.org/10.1371/journal.pcbi.0030063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847699/
https://www.ncbi.nlm.nih.gov/pubmed/17411336
http://dx.doi.org/10.1371/journal.pcbi.0030063

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