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Towards Complete Sets of Farnesylated and Geranylgeranylated Proteins
Three different prenyltransferases attach isoprenyl anchors to C-terminal motifs in substrate proteins. These lipid anchors serve for membrane attachment or protein–protein interactions in many pathways. Although well-tolerated selective prenyltransferase inhibitors are clinically available, their m...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847700/ https://www.ncbi.nlm.nih.gov/pubmed/17411337 http://dx.doi.org/10.1371/journal.pcbi.0030066 |