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Towards Complete Sets of Farnesylated and Geranylgeranylated Proteins

Three different prenyltransferases attach isoprenyl anchors to C-terminal motifs in substrate proteins. These lipid anchors serve for membrane attachment or protein–protein interactions in many pathways. Although well-tolerated selective prenyltransferase inhibitors are clinically available, their m...

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Detalles Bibliográficos
Autores principales: Maurer-Stroh, Sebastian, Koranda, Manfred, Benetka, Wolfgang, Schneider, Georg, Sirota, Fernanda L, Eisenhaber, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847700/
https://www.ncbi.nlm.nih.gov/pubmed/17411337
http://dx.doi.org/10.1371/journal.pcbi.0030066

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