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Stimulation of MAP kinase pathways after maternal IL-1β exposure induces fetal lung fluid absorption in guinea pigs

BACKGROUND: We tested the hypothesis that maternal interleukin-1β (IL-1β) pretreatment and induction of fetal cortisol synthesis activates MAP kinases and thereby affects lung fluid absorption in preterm guinea pigs. METHODS: IL-1β was administered subcutaneously daily to timed-pregnant guinea pigs...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Reshma, Li, Tianbo, Koshy, Shyny, Beard, LaMonta L, Sharma, Kapil, Carter, Ethan P, Garat, Chrystelle, Folkesson, Hans G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847817/
https://www.ncbi.nlm.nih.gov/pubmed/17386088
http://dx.doi.org/10.1186/1465-9921-8-27