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On the origin of the histone fold

BACKGROUND: Histones organize the genomic DNA of eukaryotes into chromatin. The four core histone subunits consist of two consecutive helix-strand-helix motifs and are interleaved into heterodimers with a unique fold. We have searched for the evolutionary origin of this fold using sequence and struc...

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Detalles Bibliográficos
Autores principales: Alva, Vikram, Ammelburg, Moritz, Söding, Johannes, Lupas, Andrei N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847821/
https://www.ncbi.nlm.nih.gov/pubmed/17391511
http://dx.doi.org/10.1186/1472-6807-7-17