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On the origin of the histone fold
BACKGROUND: Histones organize the genomic DNA of eukaryotes into chromatin. The four core histone subunits consist of two consecutive helix-strand-helix motifs and are interleaved into heterodimers with a unique fold. We have searched for the evolutionary origin of this fold using sequence and struc...
Autores principales: | Alva, Vikram, Ammelburg, Moritz, Söding, Johannes, Lupas, Andrei N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847821/ https://www.ncbi.nlm.nih.gov/pubmed/17391511 http://dx.doi.org/10.1186/1472-6807-7-17 |
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