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Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

The human cytosolic sulfotransfases (hSULTs) comprise a family of 12 phase II enzymes involved in the metabolism of drugs and hormones, the bioactivation of carcinogens, and the detoxification of xenobiotics. Knowledge of the structural and mechanistic basis of substrate specificity and activity is...

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Detalles Bibliográficos
Autores principales: Allali-Hassani, Abdellah, Pan, Patricia W, Dombrovski, Ludmila, Najmanovich, Rafael, Tempel, Wolfram, Dong, Aiping, Loppnau, Peter, Martin, Fernando, Thonton, Janet, Edwards, Aled M, Bochkarev, Alexey, Plotnikov, Alexander N, Vedadi, Masoud, Arrowsmith, Cheryl H
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847840/
https://www.ncbi.nlm.nih.gov/pubmed/17425406
http://dx.doi.org/10.1371/journal.pbio.0050097