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Model Structure of Human APOBEC3G

BACKGROUND: APOBEC3G (apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G) has antiretroviral activity associated with the hypermutation of viral DNA through cytosine deamination. APOBEC3G has two cytosine deaminase (CDA) domains; the catalytically inactive amino-terminal domain of A...

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Detalles Bibliográficos
Autores principales: Zhang, Kun-Lin, Mangeat, Bastien, Ortiz, Millan, Zoete, Vincent, Trono, Didier, Telenti, Amalio, Michielin, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1849894/
https://www.ncbi.nlm.nih.gov/pubmed/17440614
http://dx.doi.org/10.1371/journal.pone.0000378