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Yeast Rrp14p is required for ribosomal subunit synthesis and for correct positioning of the mitotic spindle during mitosis

Here we report that Rrp14p/Ykl082p is associated with pre-60S particles and to a lesser extent with earlier 90S pre-ribosomes. Depletion of Rrp14p inhibited pre-rRNA synthesis on both the 40S and 60S synthesis pathways. Synthesis of the 20S precursor to the 18S rRNA was largely blocked, as was matur...

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Detalles Bibliográficos
Autores principales: Oeffinger, Marlene, Fatica, Alessandro, Rout, Michael P., Tollervey, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1849896/
https://www.ncbi.nlm.nih.gov/pubmed/17272295
http://dx.doi.org/10.1093/nar/gkl824