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Modulation of CD4(+) T Cell-Dependent Specific Cytotoxic CD8(+) T Cells Differentiation and Proliferation by the Timing of Increase in the Pathogen Load

BACKGROUND: Following infection with viruses, bacteria or protozoan parasites, naïve antigen-specific CD8(+) T cells undergo a process of differentiation and proliferation to generate effector cells. Recent evidences suggest that the timing of generation of specific effector CD8(+) T cells varies wi...

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Detalles Bibliográficos
Autores principales: Tzelepis, Fanny, Persechini, Pedro M., Rodrigues, Mauricio M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1849967/
https://www.ncbi.nlm.nih.gov/pubmed/17460760
http://dx.doi.org/10.1371/journal.pone.0000393