Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer

INTRODUCTION: Tamoxifen therapy reduces the risk of recurrence and prolongs the survival of oestrogen-receptor-positive patients with breast cancer. Even if most patients benefit from tamoxifen, many breast tumours either fail to respond or become resistant. Because tamoxifen is extensively metaboli...

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Detalles Bibliográficos
Autores principales: Wegman, Pia, Elingarami, Sauli, Carstensen, John, Stål, Olle, Nordenskjöld, Bo, Wingren, Sten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851378/
https://www.ncbi.nlm.nih.gov/pubmed/17244352
http://dx.doi.org/10.1186/bcr1640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851378/
https://www.ncbi.nlm.nih.gov/pubmed/17244352
http://dx.doi.org/10.1186/bcr1640

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