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Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors

BACKGROUND: Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts. METHODS: We utilised conditioned media cultures, Western blot analysis and immunocytochemistry to investigate t...

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Detalles Bibliográficos
Autores principales: Lebret, Stephanie C, Newgreen, Donald F, Thompson, Erik W, Ackland, M Leigh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851381/
https://www.ncbi.nlm.nih.gov/pubmed/17311675
http://dx.doi.org/10.1186/bcr1656