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Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

INTRODUCTION: Cancer therapies directed at specific molecular targets in signaling pathways of cancer cells, such as tamoxifen, aromatase inhibitors and trastuzumab, have proven useful for treatment of advanced breast cancers. However, increased risk of endometrial cancer with long-term tamoxifen ad...

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Detalles Bibliográficos
Autores principales: Lin, Meng-Lay, Park, Jae-Hyun, Nishidate, Toshihiko, Nakamura, Yusuke, Katagiri, Toyomasa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851384/
https://www.ncbi.nlm.nih.gov/pubmed/17280616
http://dx.doi.org/10.1186/bcr1650