Cargando…
Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family
INTRODUCTION: Cancer therapies directed at specific molecular targets in signaling pathways of cancer cells, such as tamoxifen, aromatase inhibitors and trastuzumab, have proven useful for treatment of advanced breast cancers. However, increased risk of endometrial cancer with long-term tamoxifen ad...
Autores principales: | Lin, Meng-Lay, Park, Jae-Hyun, Nishidate, Toshihiko, Nakamura, Yusuke, Katagiri, Toyomasa |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851384/ https://www.ncbi.nlm.nih.gov/pubmed/17280616 http://dx.doi.org/10.1186/bcr1650 |
Ejemplares similares
-
Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation
por: Nakano, Ichiro, et al.
Publicado: (2005) -
Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia
por: Alachkar, Houda, et al.
Publicado: (2014) -
Computational exploration of maternal embryonic leucine zipper kinase (MELK) as a cancer drug target
por: Makki Almansour, Nahlah
Publicado: (2022) -
Maternal Embryonic Leucine Zipper Kinase (MELK): A Novel Regulator in Cell Cycle Control, Embryonic Development, and Cancer
por: Jiang, Pengfei, et al.
Publicado: (2013) -
Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer
por: Inoue, Hiroyuki, et al.
Publicado: (2016)