High-resolution crystal structure of the intramolecular d(TpA) thymine–adenine photoadduct and its mechanistic implications

A high-resolution crystal structure is reported for d(TpA)*, the intramolecular thymine–adenine photoadduct that is produced by direct ultraviolet excitation of the dinucleoside monophosphate d(TpA). It confirms the presence of a central 1,3-diazacyclooctatriene ring linking the remnants of the T an...

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Detalles Bibliográficos
Autores principales: Davies, R. Jeremy H., Malone, John F., Gan, Yu, Cardin, Christine J., Lee, Michael P.H., Neidle, Stephen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851629/
https://www.ncbi.nlm.nih.gov/pubmed/17264133
http://dx.doi.org/10.1093/nar/gkl1101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851629/
https://www.ncbi.nlm.nih.gov/pubmed/17264133
http://dx.doi.org/10.1093/nar/gkl1101

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