Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene

Expression of hTERT is the major limiting factor for telomerase activity. We previously showed that methylation of the hTERT promoter is necessary for its transcription and that CTCF can repress hTERT transcription by binding to the first exon. In this study, we used electrophoretic mobility shift a...

Descripción completa

Detalles Bibliográficos
Autores principales: Renaud, S., Loukinov, D., Abdullaev, Z., Guilleret, I., Bosman, F. T., Lobanenkov, V., Benhattar, J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851636/
https://www.ncbi.nlm.nih.gov/pubmed/17267411
http://dx.doi.org/10.1093/nar/gkl1125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851636/
https://www.ncbi.nlm.nih.gov/pubmed/17267411
http://dx.doi.org/10.1093/nar/gkl1125

Ejemplares similares