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Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats

There is an emerging consensus that secondary structures of DNA have the potential for genomic instability. Palindromic AT-rich repeats (PATRRs) are a characteristic sequence identified at each breakpoint of the recurrent constitutional t(11;22) and t(17;22) translocations in humans, named PATRR22 (...

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Detalles Bibliográficos
Autores principales: Kogo, Hiroshi, Inagaki, Hidehito, Ohye, Tamae, Kato, Takema, Emanuel, Beverly S., Kurahashi, Hiroki
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851657/
https://www.ncbi.nlm.nih.gov/pubmed/17264116
http://dx.doi.org/10.1093/nar/gkm036