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Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase
BACKGROUND: Isoprenoid precursor synthesis via the mevalonate route in humans and pathogenic trypanosomatids is an important metabolic pathway. There is however, only limited information available on the structure and reactivity of the component enzymes in trypanosomatids. Since isoprenoid biosynthe...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851959/ https://www.ncbi.nlm.nih.gov/pubmed/17397541 http://dx.doi.org/10.1186/1472-6807-7-20 |