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Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase

BACKGROUND: Isoprenoid precursor synthesis via the mevalonate route in humans and pathogenic trypanosomatids is an important metabolic pathway. There is however, only limited information available on the structure and reactivity of the component enzymes in trypanosomatids. Since isoprenoid biosynthe...

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Detalles Bibliográficos
Autores principales: Sgraja, Tanja, Smith, Terry K, Hunter, William N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851959/
https://www.ncbi.nlm.nih.gov/pubmed/17397541
http://dx.doi.org/10.1186/1472-6807-7-20