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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention

Cyclin D1 is an important regulator of cell cycle progression and can function as a transcriptionl co-regulator. The overexpression of cyclin D1 has been linked to the development and progression of cancer. Deregulated cyclin D1 degradation appears to be responsible for the increased levels of cycli...

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Detalles Bibliográficos
Autor principal: Alao, John P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851974/
https://www.ncbi.nlm.nih.gov/pubmed/17407548
http://dx.doi.org/10.1186/1476-4598-6-24