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Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA
BACKGROUND: Balancing selection operating for long evolutionary periods at a locus is characterized by the maintenance of distinct alleles because of a heterozygote or rare-allele advantage. The loci under balancing selection are distinguished by their unusually high polymorphism levels. In this rep...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852088/ https://www.ncbi.nlm.nih.gov/pubmed/17376234 http://dx.doi.org/10.1186/1741-7007-5-12 |