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Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA

BACKGROUND: Balancing selection operating for long evolutionary periods at a locus is characterized by the maintenance of distinct alleles because of a heterozygote or rare-allele advantage. The loci under balancing selection are distinguished by their unusually high polymorphism levels. In this rep...

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Detalles Bibliográficos
Autores principales: Baysal, Bora E, Lawrence, Elizabeth C, Ferrell, Robert E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852088/
https://www.ncbi.nlm.nih.gov/pubmed/17376234
http://dx.doi.org/10.1186/1741-7007-5-12