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Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen

BACKGROUND: We have developed a cell-based vaccine that features the expression of both CD80 and CD86 on the surface of a murine neuroblastoma cell line. The cellular immunity induced by this vaccine is enhanced by treatment with antibody that interferes with T-regulatory cell (Treg) function and we...

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Detalles Bibliográficos
Autores principales: Zheng, Jin, Kohler, M Eric, Chen, Qingrong, Weber, James, Khan, Javed, Johnson, Bryon D, Orentas, Rimas J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852119/
https://www.ncbi.nlm.nih.gov/pubmed/17397536
http://dx.doi.org/10.1186/1471-2172-8-4