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Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen
BACKGROUND: We have developed a cell-based vaccine that features the expression of both CD80 and CD86 on the surface of a murine neuroblastoma cell line. The cellular immunity induced by this vaccine is enhanced by treatment with antibody that interferes with T-regulatory cell (Treg) function and we...
Autores principales: | Zheng, Jin, Kohler, M Eric, Chen, Qingrong, Weber, James, Khan, Javed, Johnson, Bryon D, Orentas, Rimas J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852119/ https://www.ncbi.nlm.nih.gov/pubmed/17397536 http://dx.doi.org/10.1186/1471-2172-8-4 |
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