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Perlecan controls neurogenesis in the developing telencephalon

BACKGROUND: Perlecan is a proteoglycan expressed in the basal lamina of the neuroepithelium during development. Perlecan absence does not impair basal lamina assembly, although in the 55% of the mutants early disruptions of this lamina conducts to exencephaly, impairing brain development. The rest o...

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Detalles Bibliográficos
Autores principales: Girós, Amparo, Morante, Javier, Gil-Sanz, Cristina, Fairén, Alfonso, Costell, Mercedes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852307/
https://www.ncbi.nlm.nih.gov/pubmed/17411441
http://dx.doi.org/10.1186/1471-213X-7-29