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Perlecan controls neurogenesis in the developing telencephalon
BACKGROUND: Perlecan is a proteoglycan expressed in the basal lamina of the neuroepithelium during development. Perlecan absence does not impair basal lamina assembly, although in the 55% of the mutants early disruptions of this lamina conducts to exencephaly, impairing brain development. The rest o...
Autores principales: | Girós, Amparo, Morante, Javier, Gil-Sanz, Cristina, Fairén, Alfonso, Costell, Mercedes |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852307/ https://www.ncbi.nlm.nih.gov/pubmed/17411441 http://dx.doi.org/10.1186/1471-213X-7-29 |
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