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Cyclin E and CDK2 Repress the Terminal Differentiation of Quiescent Cells after Asymmetric Division in C. elegans

Coordination between cell proliferation and differentiation is important in normal development and oncogenesis. These processes usually have an antagonistic relationship, in that differentiation is blocked in proliferative cells, and terminally differentiated cells do not divide. In some instances,...

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Detalles Bibliográficos
Autores principales: Fujita, Masaki, Takeshita, Hisako, Sawa, Hitoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852333/
https://www.ncbi.nlm.nih.gov/pubmed/17476329
http://dx.doi.org/10.1371/journal.pone.0000407