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Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase
Protein kinases are critical to cellular signalling and post-translational gene regulation, but their biological substrates are difficult to identify. We show that cyclin-dependent kinase (CDK) consensus motifs are frequently clustered in CDK substrate proteins. Based on this, we introduce a new com...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852407/ https://www.ncbi.nlm.nih.gov/pubmed/17316440 http://dx.doi.org/10.1186/gb-2007-8-2-r23 |