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Analysis of IL-12 p40 subunit gene and IFN-γ G5644A polymorphisms in Idiopathic Pulmonary Fibrosis

BACKGROUND: Genes encoding cytokine mediators are prime candidates for genetic analysis in conditions with T-helper (Th) cell disease driven imbalance. Idiopathic Pulmonary Fibrosis (IPF) is a predominantly Th2 mediated disease associated with a paucity of interferon-gamma (IFN-γ). The paucity of IF...

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Detalles Bibliográficos
Autores principales: Latsi, Panagiota, Pantelidis, Panagiotis, Vassilakis, Dimitris, Sato, Hiroe, Welsh, Kenneth I, du Bois, Roland M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC185252/
https://www.ncbi.nlm.nih.gov/pubmed/12914676
http://dx.doi.org/10.1186/1465-9921-4-6