Novel APC mutations in Czech and Slovak FAP families: clinical and genetic aspects

BACKGROUND: Germline mutations in the adenomatous polyposis gene (APC) result in familial adenomatous polyposis (FAP). FAP is an autosomal dominantly inherited disorder predisposing to colorectal cancer. Typical FAP is characterized by hundreds to thousands of colorectal adenomatous polyps and by se...

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Detalles Bibliográficos
Autores principales: Stekrova, Jitka, Sulova, Martina, Kebrdlova, Vera, Zidkova, Katerina, Kotlas, Jaroslav, Ilencikova, Denisa, Vesela, Kamila, Kohoutova, Milada
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853078/
https://www.ncbi.nlm.nih.gov/pubmed/17411426
http://dx.doi.org/10.1186/1471-2350-8-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853078/
https://www.ncbi.nlm.nih.gov/pubmed/17411426
http://dx.doi.org/10.1186/1471-2350-8-16

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