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Association of TGFβ1, TNFα, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians

BACKGROUND: Cytokines play an important role in the development of diabetic chronic renal insufficiency (CRI). Transforming growth factor β1 (TGF β1) induces renal hypertrophy and fibrosis, and cytokines like tumor necrosis factor-alpha (TNFα), chemoattractant protein-1 (MCP-1), and regulated upon a...

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Detalles Bibliográficos
Autores principales: Prasad, Pushplata, Tiwari, Arun K, Kumar, KM Prasanna, Ammini, AC, Gupta, Arvind, Gupta, Rajeev, Thelma, BK
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853079/
https://www.ncbi.nlm.nih.gov/pubmed/17428349
http://dx.doi.org/10.1186/1471-2350-8-20